Full Kit 10 vials of Semax 10mg per vial –
May need extra delivery time if not in stock when ordered
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from a fragment of adrenocorticotropic hormone (ACTH), developed to provide neurotrophic and nootropic effects without the hormonal activity of ACTH. It is primarily used for its cognitive-enhancing properties, including improved memory, learning, focus, and mental clarity, and is known for its neuroprotective and neuroregenerative effects.
Key Properties and Mechanisms
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Neurotrophic & Nootropic Effects: Semax enhances brain-derived neurotrophic factor (BDNF) expression and activates the TrkB receptor in the hippocampus, supporting neurogenesis, synaptic plasticity, and long-term cognitive function.
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Neuroprotection: It protects neurons against oxidative stress, hypoxia, glutamate toxicity, and heavy metal damage. Studies show it reduces neuronal cell death and supports mitochondrial stability.
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Immune and Vascular Modulation: Semax influences immune response genes and promotes vascular system function, particularly relevant in stroke and cerebral ischemia models.
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Copper Chelation: It forms stable complexes with copper(II), reducing copper-induced cytotoxicity in neural cells, suggesting potential in neurodegenerative conditions linked to metal ion dysregulation.
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Opioid Receptor Interaction: Recent research indicates Semax targets the μ-opioid receptor (Oprm1), promoting deubiquitination and functional recovery after spinal cord injury in mice.





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